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Interpretations should be rendered accordingly, urti the reduced loss aversion in heroin users was robust across all models we tested. In urti, by recruiting relatively pure amphetamine and heroin users in protracted abstinence and by parcellating their decision-making performance into distinct neurocognitive urti by using computational modeling and Bayesian tools, we revealed that heroin urti displayed reduced loss aversion relative to HC while being in protracted abstinence.

Future studies utilizing other experimental paradigms probing different aspects of decision-making and computational models will be necessary urti examine which mechanisms may be at play in the decision-making performance of heroin and amphetamine users at different stages of the addiction cycle.

This publication was made possible by R01DA021421 grant urti the National Institute on Drug Abuse (NIDA) and the Fogarty International Center (FIC) to Jasmin Vassileva. Its contents are solely the responsibility of the authors and do not necessarily represent urti official views of the National Institutes of Health (NIH).

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